He died in China while undergoing Kidney treatment, producer Socrates Safo has confirmed.
His death follows that of the actors guild president, Eddie Coffie who died late last year.
Last year, on January 21, 2015, according to a report by myjoyonline.com, Nii Odoi Mensah needed $300 weekly to stay live.
Doctors declared both kidneys incapable of performing their key functions effectively to keep him alive.
To stay alive, the actor had to spend $300 weekly on dialysis.